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Monday, October 24, 2011

The oral dosage forms are the most popular way of
taking medication despite having some
disadvantages like slow absorption and thus onset of
action is prolong. This can be overcome by
administrating the drug in liquid from but, many APIs
have limited level of stability in liquid form. So,
effervescent tablets acts as an alternative dosage
form. The tablet is added into a glass of water just
before administration and the drug solution or
dispersion is to be drunk immediately. The tablet is
quickly broken apart by internal liberation of CO2 in
water due to interaction between tartaric acid and
citric acid with alkali metal carbonates or
bicarbonates in presence of water
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