Drug delivery research is clearly moving from the micro- to the nanosize scale. Nanotechnology is therefore emerging as a field in medicine that is expected to elicit significant therapeutic benefits. The development of effective nanodelivery systems capable of carrying a drug specifically and safely to a desired site of action is one of the most challenging tasks of pharmaceutical formulation investigators. They are attempting to reformulate and add new indications to the existing blockbuster drugs to maintain positive scientific outcomes and therapeutic breakthroughs. The nanodelivery systems mainly include nanoemulsions, lipid or polymeric nanopar- ticles, and liposomes. Nanoemulsions are primarily used as vehicles of lipophilic drugs following intravenous administration. On the other hand, the ultimate objec- tive of the other nanodelivery systems is to alter the normal biofate of potent drug molecules in the body following their intravenous administration to markedly improve their efficacy and reduce their potential intrinsic severe adverse effects.
Sunday, May 26, 2013
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